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MALE AND FEMALE (SEX) ANOMALIES / EXCEPTIONS TO XX/XY RULE

MALE AND FEMALE (SEX) ANOMALIES / EXCEPTIONS TO XX/XY RULE

Important: Sex anomalies are biological and are separate from mental disorders such as "transsexualism" - which is the root of "transgender" "non-binary"

Image of X sperm fertilizing an X egg (XX female) and a Y sperm fertilizing another X egg (XY male)

XX/XY RULE

  • If a human has XX sex chromosomes then she is a female. 
  • If a human has XY chromosomes then he is male. 
  • The embryo then receives hormones to cement his or her sex.
  • There are RARE anomalies to the "XX / XY RULE," but each human is still either a male or a female
  • NOTE: Sex anomalies are separate from the mental disorder of transsexualism (currently referred to as "transgender") and it's mutation "non-binary." 

A SHORT LIST OF THE INNUMERABLE SEX ANOMALIES:

A SHORT LIST OF THE INNUMERABLE SEX ANOMALIES:

SEX ANOMALIES - CHROMOSOMAL

Image of medical diagnoses for sex chromosome anomalies, eg Klinefelter, XYY and Turner Syndromes

  • Roughly one in 500 individuals have a sex chromosome anomaly.
  • These individuals still present as either male (male external genitalia) or female (female external genitalia) 
  • These anomalies are assigned medical diagnoses 
  • Signs and symptoms (S/S) occur on a spectrum and some individuals do not have any observable S/S until puberty
  • Unfortunately, sex chromosome anomalies are very often linked to numerous comorbidities such as a learning disability and impaired motor (muscle) function

Diagnosis ICD-10-Codes Q96-Q99

Klinefelter's Syndrome - XXY sex chromosomes

  • Diagnosis: ICD-10-Code Q98.4
  • One in 1,000 live male births

Learn More
Case Report: a 33-year-old male with Klinefelter's Syndrome

XXYY Syndrome

  • Diagnosis: ICD-10-Code Q98.9
  • One in 850 to 3,000 male births

Learn more
Case Report: a 7-year-old male with XXYY Syndrome

XYY Syndrome

  • Diagnosis: ICD-10-Code Q98.5
  • One in 1,000 male births
  • Most affected individuals are never diagnosed

Learn more
Case Report: a 13-year-old male with XYY Syndrome

XYYY Syndrome

  • Diagnosis: ICD-10-Code Q98.9
  • One in 18,000 to 40,000 male births

Learn more
Case Report: a male with XYYY Syndrome

Turner Syndrome - one X sex chromosome (no other sex chromosomes)

  • Diagnosis: ICD-10-Code Q96.0-Q96.9
  • One in 2,500 live female births

Learn more
Case Report: a 61-year-old female with Turner Syndrome

Trisomy X Syndrome - XXX sex chromosomes

  • Diagnosis: ICD-10-Code Q97.0
  • One in 1,000 live female births
  • Learn more

Case Report: a 21-year-old female with Trisomy X

SEX ANOMALIES - Androgen Insensitivity Syndrome (AIS)

Androgen Insensitivity Syndrome (AIS)

  • AIS occurs in perhaps one in 100,000 individuals 
  • There are 3 primary types of AIS: Complete AIS (CAIS), Partial AIS (PAIS), and Mild AIS (MAIS)

Partial (PAIS) and Mild (MAIS) Androgen Insensitivity Syndrome

  • Diagnosis: ICD-10-Code E34.5 Androgen insensitivity syndrome (AIS) 
  • Results in a partial failure of normal masculinization of the external genitalia and the affected person can present as a male or female or ambiguous

Learn More

Complete androgen insensitivity syndrome (CAIS), aka Morris Syndrome

  • Diagnosis: ICD-10-Code E34.51 Complete androgen insensitivity syndrome (CAIS) 
  • Has male internal sex organs (testes) that are undescended, which means they are located in the pelvis or abdomen instead of outside the body. 
  • Do not have a uterus, do not menstruate, are infertile
  • Failure of normal masculinization of the external genitalia and the affected person presents as a female
  • Sparse or absent hair in the pubic area and under the arms.

Case Report: Three sisters with Morris Syndrome
Case Report: 21 yr-old-person with Morris Syndrome

SEX ANOMALIES - XY FEMALE - SWYER SYNDROME

Photo of model Hanne Gaby Odiele, who is intersex (has XY sex chromosomes but presents as female)

  • Diagnosis: ICD-10-Code Q99.1
  • Individual has XY sex chromosomes, but presents as a female
  • Occurs in one in 20,000 live births 
  • The cause is often unknown
  • However, in about 15% of cases it is due to a mutation in the  SRY gene 
  • The SRY gene, located on the Y chromosome, provides instructions for making a protein called sex-determining region 

Learn More
Case Report: Hanne Gaby Odiele (pictured)

  • Gaby Odiele has Swyer Syndrome (XY female) and describes herself as "intersex"
  • Gaby, who is a model, has stated that some "intersex" people "leave medical care altogether because they are so angry at what physicians did to them [surgery to appear more female or more male] before they were the age of consent."
  • Gaby's statement supports the inappropriateness of "gender affirming care" in children because a person does not reach the age of consent until age 18. 
  • Due to her views, Gaby would be labeled "transphobic" by the "transgender" community.

Case Report: a 27-yr-old person with Swyer Syndrome
Case Report: a 50-yr-old Person with Swyer Syndrome

SEX ANOMALIES - XX MALE - DE LA CHAPELLE SYNDROME

  • Diagnosis: ICD-10-Code Q93.59
  • One in 80,000 live births
  • While there are two X sex chromosomes in each cell, the person invariably has male external genitallia, ranging from normal to atypical with associated testosterone deficiency.
  • The internal sex organs do not form normally and might not even be present.
  • The testes are small and undescended  (cryptorchidism) or the urethra opening is on the underside of the penis (hypospadias). 
  • A small number of affected people have ambiguous genitalia.
  • The cause of de la Chapelle syndrome is a random event during the formation of sperm cells in the affected person's father. A translocation causes the SRY gene to be misplaced,onto an X chromosome. If a fetus is conceived from a sperm cell with an X chromosome bearing the SRY gene, it will develop as a male despite not having a Y chromosome.

Reference
Reference
Learn More
Case Report: 30 yr-old person with de la Chapelle Syndrome

SEX ANOMALIES - Ambiguous genitalia

Diagnosis: ICD-10-CodeQ56.4 Indeterminate sex, unspecified. Ambiguous genitalia

Ambiguous Genitalia, aka, Disorders of Sexual Differentiation (DSD)

Black and white image of ambiguous genitalia from normal male to ambiguous types to normal female

The external genitalia are neither fully male nor female

Diagnosis: ICD-10-CodeQ56.4 Indeterminate sex, unspecified. Ambiguous genitalia

  • Ambiguous genitalia affect approximately 1 in 5,000 live births. 
  • The degree of ambiguity varies greatly. 
  • In recent history, pediatricians use a Phall-O-Meter (pictured) to assign sex if genitalia is ambiguous.
  • Up until fairly recently, if an infant presented with severe genital ambiguity, the pediatrician and parents might agree to have surgery performed to align the infant's sex organs to more closely align with one sex. 
  • Eventually, there was public outcry that this is inhumane and the child should be given the freedom to decide for his/her own course of action when an adult and this practice was sidelined. 
  • Ironically,  transgender ideology supports children as young as two or three deciding if they are a boy or girl.

Reference
Learn More

Case Report: an Infant with Ambiguous Genitalia

4 photos: a) clitoromegaly b) post-op vaginoplasty c) male and female ovotestis d) gross specimen

(a) Female external genitalia with clitoromegaly (b) Postoperative photograph after vaginoplasty and reduction of the enlarged clitoris (c) Gross specimen showing female (♀) and male (♂) parts of ovotestis (d) Cut surface of gross specimen showing grayish white, yellowish areas intersected by darker areas

Research Article

Case Report: an Infant with Ambiguous Genitalia

Photo of close-up of infant with bilateral gonads and clitoromegaly (draping used)

Bilateral gonads and clitoromegaly

Research Article

Hermaphroditism

  • In severe Ambiguous Genitalia, the person has both ovarian and testicular tissue. When this occurs, the person is diagnosed with Hermaphroditism.
  • Less than 2% of those born with Ambiguous Genitalia meet the diagnostic criteria for Hermaphroditism (Source) 
  • Despite the severity of the sex anomaly Hermaphroditism, the person tends to present as either a male or female. 
  • Diagnostic ICD-10-codes: 
  • Q56.1 Male pseudohermaphroditism, not elsewhere classified 
  • Q56.2 Female pseudohermaphroditism, not elsewhere classified 
  • Q56.3 Pseudohermaphroditism, unspecified 

Q56 ICD-10-codes

Hermaphrodite rebranded Intersex by transgender activists

  • In the 1940s, it was suggested the term hermaphrodite be replaced with the term intersex, which had been coined by Richard Goldschmidt in 1917. (Source)
  • Despite the term Intersex being misleading (because each human is either a male or a female), more people began to advocate for the term. 
  • A notable intersex and transgender activist is Morgan Carpenter  Morgan was born with a sex anomaly and a surgery was performed on him when he was an infant to attempt to mask it. He did not learn he was born with a sex anomaly until he was an adult. (Source) Because surgery was performed on him, it is logical that he was born with ambiguous genitalia. 
  • In July 2013, Morgan created an "intersex" flag (pictured).
  • In 2021,Valentino Vecchietti incorporated the intersex flag into the rainbow pride flag (Source). The new flag has been heavily marketed by transgender activists in an attempt to give the nonsensical transgender ideology credibility.


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